Damage to the bone marrow, by way of displacing the normal marrow cells with increasing numbers of malignant cells, results in a lack of blood platelets, which are important in the blood clotting process. This means people with leukemia may become bruised, bleed excessively, or develop pinprick bleeds (petechiae).
White blood cells, which are involved in fighting pathogens, may be suppressed or dysfunctional, putting the patient at the risk of developing infections.
Finally, the red blood cell deficiency leads to anemia, which may cause dyspnea. All symptoms may also be attributable to other diseases; for diagnosis, blood tests and a bone marrow biopsy are required.
Some other related symptoms
- Fever, chills, and other flu-like symptoms
- Weakness and fatigue
- Loss of appetite and/or weight
- Swollen or bleeding gums
- Neurological symptoms (headache)
- Enlarged liver and spleen
Reference by Wikipedia
http://en.wikipedia.org/wiki/Leukemia
